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U.S. Biology trio wins Nobel Medicine prize

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United States geneticists, Jeffrey C. Hall, Michael Rosbash, and Michael W. Young were awarded the Nobel Medicine Prize on Monday for shedding light on the internal biological clock that governs the wake-sleep cycles of most living things.

“Their discoveries explain how plants, animals and humans adapt their biological rhythm so that it is synchronised with the Earth’s revolutions,” the Nobel Assembly announced.

Life on Earth is adapted to the rotation of our planet. For many years, scientists have known that living organisms, including humans, have an internal clock that help them anticipate and adapt to the rhythm of the day.

Hall, 72, Rosbash, 73, and Young, 68, “were able to peek inside our biological clock and elucidate its inner workings,” said the Nobel Assembly.

The clock influences such biological functions as hormone levels, sleep, body temperature and metabolism.

It is what causes jetlag — when our internal clock and external environment move out of sync when we change time zones.

Using the fruit fly as a model organism, this year’s laureates isolated a gene that controls the daily biological rhythm.

“They showed that this gene encodes a protein that accumulates in the cell during the night and is then degraded during the day,” the Nobel team said.

“Subsequently they identified additional protein components of this machinery, exposing the mechanism governing the self-sustaining clockwork inside the cell.”

The trio will share the prize sum of nine million Swedish kronor (about $1.1 million or 937,000 euros).

Last year, Yoshinori Ohsumi of Japan won the prestigious prize for his work on autophagy — a process whereby cells “eat themselves”, which when disrupted can cause Parkinson’s and diabetes.

– AFP

FOREIGN

“Gladiator II” Becomes Denzel Washington’s Most Successful Movie With $320 Million Worldwide Gross

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Gladiator II is Denzel Washington's Most Successful Movie | fab.ng
Gladiator II has become the highest-grossing film of Ridley Scott’s career. The movie features the legendary actor Denzel Washington.

Known as one of Hollywood’s most respected figures, Washington has built an extraordinary career filled with iconic performances and critical acclaim.

His influence extends far beyond Hollywood, earning him global admiration. However, despite his illustrious career, Washington has not always been the first name associated with record-breaking box office success compared to some of his contemporaries.

His recent collaboration with Ridley Scott has now changed that narrative. Gladiator II has shattered expectations, becoming Washington’s highest-grossing film worldwide.

The movie has earned an impressive $320.2 million globally. This surpasses his previous record-holder, American Gangster, which grossed $267.9 million.

This milestone solidifies Gladiator II as Washington’s most financially successful film directed by Scott.

Domestically, American Gangster has maintained its position as Washington’s top-earning film for 17 years, with a domestic gross of $130.1 million.

However, this record may soon be eclipsed by Gladiator II, which has already reached $111.4 million domestically and continues to draw large audiences.

The success of Gladiator II marks a significant achievement in Washington’s career. It shows his enduring appeal and the powerful collaboration with Ridley Scott.

 

This box office triumph not only highlights Washington’s versatility and star power but also sets a new benchmark for future projects.

Fans and industry insiders alike are watching closely, anticipating how far this latest release will go in redefining the actor’s box office legacy.

READ ALSO: Gladiator II” Records ₦99.1 Million In Its Opening Weekend At The Nigerian Box Office

Throughout his decades-long film career, Washington has taken on a variety of action roles, many of which have been box-office successes.

The Equaliser franchise, for instance, has grossed approximately $190 million worldwide per installment.

Even some of his less critically acclaimed films, such as 2012’s Safe House, achieved significant commercial success, grossing $208.1 million against a budget of $85 million.

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FOREIGN

Lee Min-Ho Returns To The Big Screens In Netflix’s “When The Stars Gossip”

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Lee Min-Ho back to the screen in When The Stars Gossip | fab.ng

Lee Min-ho is set to make a triumphant return to the big screens with Netflix’s upcoming South Korean series When The Stars Gossip.

After a well-planned hiatus, the iconic actor will star in this highly anticipated sci-fi romance alongside Gong Hyo-jin.

The series will premiere globally on January 4, 2025. Netflix K-Content announced it with exclusive first-look images that tease a captivating narrative exploring love and life among the stars.

In the series, Min-ho takes on the role of an OB-GYN who becomes a space tourist. Meanwhile, Gong portrays a space mission commander. Their characters promise an exciting dynamic that blends romance and adventure in an interstellar setting.

Renowned as one of South Korea’s most celebrated actors, Lee Min-ho rose to international fame with his breakout role as the charismatic Gu Jun-Pyo in the 2009 drama Boys Before Flowers.

His performance earned widespread acclaim and established him as a key figure in the global Hallyu wave. Over the years, he has enthralled audiences with his performances in hit dramas. These dramas are The Heirs (2013), Legend of the Blue Sea (2016), and The King: Eternal Monarch (2020).

Known for his selective approach to roles, Min-ho consistently curates projects that highlight his versatility, leaving fans eagerly anticipating his next move.

His most recent major project, Apple TV+’s Pachinko, showcased his exceptional acting skills. In seasons one (2022) and two (2024), Min-ho delivered a critically acclaimed performance as Koh Hansu, a morally complex and nuanced character. This role further cemented his reputation as a versatile and skilled actor.

Lee Min-ho’s deliberate approach to choosing projects has elevated the anticipation for When The Stars Gossip. Fans are thrilled to see him return to the small screen in a fresh and compelling narrative.

The series boasts an impressive supporting cast. They include Gong Hyo-jin (When the Camellia Blooms), Oh Jung-se (It’s Okay to Not Be Okay), Han Ji-Eun (Be Melodramatic), Kim Joo-hun (Castaway Diva), Lee El (My Liberation Notes), Lee Cho-hee (Once Again), and Heo Nam-jun (Sweet Home).

Indeed, the show promises to captivate audiences worldwide with its unique mix of sci-fi and romance.

Check out more movie updates here.

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INTERNATIONAL

“Gladiator II” Records ₦99.1 Million In Its Opening Weekend At The Nigerian Box Office

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Gladiator II records ₦99.1 million in its opening weekend | fab.ng
Ridley Scott’s Gladiator II has taken the Nigerian box office by storm, earning an impressive ₦99.1 million during its opening weekend. This remarkable feat positions the epic as the second-highest opening film of the year in Nigeria.

Before its weekend release, Gladiator II generated significant momentum. On Wednesday, it earned ₦8.13 million, followed by ₦8.96 million on Thursday.

An advanced screening earlier in the week pulled in ₦17 million across two days, showcasing strong local anticipation. These milestones cement the film as one of 2024’s top-performing titles in Nigeria.

The sequel, directed by Ridley Scott, follows Lucius, the nephew of Maximus, the heroic protagonist of the original Gladiator. After ruthless Roman emperors seize his home, Lucius embraces the life of a gladiator to seek revenge and restore Rome’s glory.

The film delves into timeless themes of vengeance and redemption, set against the backdrop of ancient Rome.

Featuring a star-studded cast including Paul Mescal, Pedro Pascal, Joseph Quinn, and Denzel Washington, Gladiator II has captivated Nigerian audiences. The movie’s strong local performance underscores the growing appeal of global cinema in Nigeria.

On the international stage, Gladiator II debuted with an estimated $87 million, marking the largest opening weekend for any Ridley Scott film.

This success highlights the sequel’s long-awaited arrival, nearly two decades after Gladiator premiered in 2000. The development of the sequel spanned years, with numerous script drafts considered before the final version emerged in 2018. Paul Mescal joined the cast in early 2023, solidifying the project’s momentum.

Written by David Scarpa (Napoleon) in collaboration with Peter Craig, Gladiator II was distributed by Paramount Pictures.

Filming took place between June 2023 and January 2024, delivering a cinematic masterpiece that bridges nostalgia and modern storytelling.

Check out more movie updates here.

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